Researchers at the University of Iowa and Stanford University have developed a new tool that allows scientists to safely and accurately measure the effect of transcranial magnetic stimulation (TMS) on the activity of deep brain structures. The new technique, known as TMS-iEEG (intracranial electrocorticography), is providing hard data on how TMS works and may lead to improvements in the…
Research and Education
Research and Education
University of Iowa Health Care is among the first sites in the country to participate in a phase 3 clinical trial to test a new, personalized vaccine for patients with high-risk melanoma. The study will combine individualized mRNA vaccines with the immunotherapy pembrolizumab to determine if the combination is safe and does a better job than pembrolizumab alone at preventing melanoma from…
The U.S. Food and Drug Administration (FDA) approved a medical technology created by a University of Iowa faculty member to treat atrial fibrillation (Afib) in January 2024. Now, physicians in the cardiac electrophysiology division of UI Health Care are the first in the state to begin using the technology in clinical care. “Pulse field ablation, particularly Farapulse, offers a safe, more…
Extremely premature infants who were fed donated breast milk had less than half the rate of a life-threatening disease than those fed formula, according to a new study led by the University of Iowa. Researchers also found extremely preterm infants—classified as babies born before 29 weeks—who were fed donor milk experienced the same neurological development as those who were fed formula…
Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon monoxide-infused foam that boosted the effectiveness of the therapy, known as autophagy inhibition, in mice and human cells. The findings were recently published in the journal…
A University of Iowa-led team of international neuroscientists have obtained the first direct recordings of the human brain in the minutes before and after a brain hub crucial for language meaning was surgically disconnected. The results reveal the importance of brain hubs in neural networks and the remarkable way in which the human brain attempts to compensate when a hub is lost, with immediacy…
University of Iowa Health Care is one of nine leading research centers participating in a new clinical trial testing the ability of an off-patent drug to slow or prevent osteoarthritis. The first-of-its-kind trial is sponsored and directed by the Arthritis Foundation and will focus on patients at high risk for post-traumatic osteoarthritis (PTOA) in the knee. Osteoarthritis (OA) affects over 30…
Twist. Pop. Pain. It’s a combination that any athlete—young or old, professional or weekend warrior—knows and dreads as a likely indication of a torn ACL. Rupture of the anterior cruciate ligament (ACL), which stabilizes the knee joint, is an extremely common injury, affecting between 100,000 to 200,000 people in the U.S. every year. It is also a significant injury, often requiring surgery and…
UI Health Care researchers are collaborating with colleagues across the nation and the world to advance science and medicine. In just the past two weeks, UI researchers published new findings in high impact journals on the following topics: Treatment for metastatic eye cancer (NEJM). Molecular underpinnings of eye aging and disease (Cell). How a fungus adapts to infect human hosts (Nature…
A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface. This function is exactly the opposite of what was expected of these cells and may have implications for cystic fibrosis (CF) lung disease. Five years ago, scientists reported the unexpected discovery that ionocytes—a cell type…