Jan. 10, 2024 | medicine.uiowa.edu
Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon monoxide-infused foam that boosted the effectiveness of the therapy, known as autophagy inhibition, in mice and human cells. The findings were recently published in the journal…
Dec. 04, 2023 | medicine.uiowa.edu
A University of Iowa-led team of international neuroscientists have obtained the first direct recordings of the human brain in the minutes before and after a brain hub crucial for language meaning was surgically disconnected. The results reveal the importance of brain hubs in neural networks and the remarkable way in which the human brain attempts to compensate when a hub is lost, with immediacy…
Nov. 09, 2023 | medicine.uiowa.edu
University of Iowa Health Care is one of nine leading research centers participating in a new clinical trial testing the ability of an off-patent drug to slow or prevent osteoarthritis. The first-of-its-kind trial is sponsored and directed by the Arthritis Foundation and will focus on patients at high risk for post-traumatic osteoarthritis (PTOA) in the knee. Osteoarthritis (OA) affects over 30…
Oct. 31, 2023 | uihc.org
Twist. Pop. Pain. It’s a combination that any athlete—young or old, professional or weekend warrior—knows and dreads as a likely indication of a torn ACL. Rupture of the anterior cruciate ligament (ACL), which stabilizes the knee joint, is an extremely common injury, affecting between 100,000 to 200,000 people in the U.S. every year. It is also a significant injury, often requiring surgery and…
Oct. 27, 2023 | medicine.uiowa.edu
UI Health Care researchers are collaborating with colleagues across the nation and the world to advance science and medicine. In just the past two weeks, UI researchers published new findings in high impact journals on the following topics: Treatment for metastatic eye cancer (NEJM). Molecular underpinnings of eye aging and disease (Cell). How a fungus adapts to infect human hosts (Nature…
Oct. 19, 2023 | medicine.uiowa.edu
A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface. This function is exactly the opposite of what was expected of these cells and may have implications for cystic fibrosis (CF) lung disease. Five years ago, scientists reported the unexpected discovery that ionocytes—a cell type…
Oct. 03, 2023 | medicine.uiowa.edu
New findings may take scientists a step closer to understanding what causes SUDEP—Sudden Unexpected Death in Epilepsy—a rare but fatal complication of epilepsy. There are about 3,000 deaths from SUDEP each year in the U.S. The biggest risk factor is epilepsy that is not well controlled with medication or surgery, but the exact cause of SUDEP is not known. However, increasing evidence suggests…
Sep. 18, 2023 | medicineiowa.org
An out-of-body experience. That’s how Cody Purvis describes losing nearly 75% of the hair on her head as a result of the autoimmune disease alopecia areata. “The person that I looked at in the mirror every day was just not who I was,” says Purvis, a pet boarding and grooming business owner in Kanawha, Iowa. In alopecia areata, the body’s immune system attacks hair follicles. It can result in…
Feb. 21, 2020
While career opportunities in STEM (science, technology, engineering, and math) are on the rise, women remain vastly underrepresented in these fields.University of Iowa Health Care experts are helping change that, through a unique educational program aimed at getting girls interested in STEM. Girls Go STEM is an annual event intended to inspire the next generation of health care professionals...